diff --git a/hack/test/e2e-run.sh b/hack/test/e2e-run.sh
index e7a2c5420b..4328837127 100755
--- a/hack/test/e2e-run.sh
+++ b/hack/test/e2e-run.sh
@@ -12,4 +12,4 @@ cd /tests/integration/container
 
 echo "Run integration-cli DockerSuite tests"
 cd /tests/integration-cli
-./test.main -test.v -check.v -check.f DockerSuite
+./test.main -test.v -check.v -check.f "DockerSuite|DockerNetworkSuite"
diff --git a/integration-cli/docker_cli_network_unix_test.go b/integration-cli/docker_cli_network_unix_test.go
index bdb184fa79..c4da8ae2e2 100644
--- a/integration-cli/docker_cli_network_unix_test.go
+++ b/integration-cli/docker_cli_network_unix_test.go
@@ -353,6 +353,8 @@ func (s *DockerNetworkSuite) TestDockerNetworkRmPredefined(c *check.C) {
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkLsFilter(c *check.C) {
+	// E2E: Test assumes clean network environment.
+	testRequires(c, NotE2E)
 	testNet := "testnet1"
 	testLabel := "foo"
 	testValue := "bar"
@@ -626,6 +628,7 @@ func (s *DockerNetworkSuite) TestDockerNetworkConnectDisconnect(c *check.C) {
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkIPAMMultipleNetworks(c *check.C) {
+	testRequires(c, SameHostDaemon)
 	// test0 bridge network
 	dockerCmd(c, "network", "create", "--subnet=192.168.0.0/16", "test1")
 	assertNwIsAvailable(c, "test1")
@@ -666,6 +669,7 @@ func (s *DockerNetworkSuite) TestDockerNetworkIPAMMultipleNetworks(c *check.C) {
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkCustomIPAM(c *check.C) {
+	testRequires(c, SameHostDaemon)
 	// Create a bridge network using custom ipam driver
 	dockerCmd(c, "network", "create", "--ipam-driver", dummyIPAMDriver, "br0")
 	assertNwIsAvailable(c, "br0")
@@ -681,6 +685,7 @@ func (s *DockerNetworkSuite) TestDockerNetworkCustomIPAM(c *check.C) {
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkIPAMOptions(c *check.C) {
+	testRequires(c, SameHostDaemon)
 	// Create a bridge network using custom ipam driver and options
 	dockerCmd(c, "network", "create", "--ipam-driver", dummyIPAMDriver, "--ipam-opt", "opt1=drv1", "--ipam-opt", "opt2=drv2", "br0")
 	assertNwIsAvailable(c, "br0")
@@ -693,6 +698,7 @@ func (s *DockerNetworkSuite) TestDockerNetworkIPAMOptions(c *check.C) {
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkNullIPAMDriver(c *check.C) {
+	testRequires(c, SameHostDaemon)
 	// Create a network with null ipam driver
 	_, _, err := dockerCmdWithError("network", "create", "-d", dummyNetworkDriver, "--ipam-driver", "null", "test000")
 	c.Assert(err, check.IsNil)
@@ -798,6 +804,7 @@ func (s *DockerNetworkSuite) TestDockerNetworkIPAMInvalidCombinations(c *check.C
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkDriverOptions(c *check.C) {
+	testRequires(c, SameHostDaemon)
 	dockerCmd(c, "network", "create", "-d", dummyNetworkDriver, "-o", "opt1=drv1", "-o", "opt2=drv2", "testopt")
 	assertNwIsAvailable(c, "testopt")
 	gopts := remoteDriverNetworkRequest.Options[netlabel.GenericData]
@@ -983,6 +990,7 @@ func (s *DockerNetworkSuite) TestDockerNetworkLinkOnDefaultNetworkOnly(c *check.
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkOverlayPortMapping(c *check.C) {
+	testRequires(c, SameHostDaemon)
 	// Verify exposed ports are present in ps output when running a container on
 	// a network managed by a driver which does not provide the default gateway
 	// for the container
@@ -1009,7 +1017,7 @@ func (s *DockerNetworkSuite) TestDockerNetworkOverlayPortMapping(c *check.C) {
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkDriverUngracefulRestart(c *check.C) {
-	testRequires(c, DaemonIsLinux, NotUserNamespace)
+	testRequires(c, DaemonIsLinux, NotUserNamespace, SameHostDaemon)
 	dnd := "dnd"
 	did := "did"
 
@@ -1050,6 +1058,7 @@ func (s *DockerNetworkSuite) TestDockerNetworkDriverUngracefulRestart(c *check.C
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkMacInspect(c *check.C) {
+	testRequires(c, SameHostDaemon)
 	// Verify endpoint MAC address is correctly populated in container's network settings
 	nwn := "ov"
 	ctn := "bb"
@@ -1115,6 +1124,7 @@ func verifyContainerIsConnectedToNetworks(c *check.C, d *daemon.Daemon, cName st
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkMultipleNetworksGracefulDaemonRestart(c *check.C) {
+	testRequires(c, SameHostDaemon)
 	cName := "bb"
 	nwList := []string{"nw1", "nw2", "nw3"}
 
@@ -1133,6 +1143,7 @@ func (s *DockerNetworkSuite) TestDockerNetworkMultipleNetworksGracefulDaemonRest
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkMultipleNetworksUngracefulDaemonRestart(c *check.C) {
+	testRequires(c, SameHostDaemon)
 	cName := "cc"
 	nwList := []string{"nw1", "nw2", "nw3"}
 
@@ -1159,7 +1170,7 @@ func (s *DockerNetworkSuite) TestDockerNetworkRunNetByID(c *check.C) {
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkHostModeUngracefulDaemonRestart(c *check.C) {
-	testRequires(c, DaemonIsLinux, NotUserNamespace)
+	testRequires(c, DaemonIsLinux, NotUserNamespace, SameHostDaemon)
 	s.d.StartWithBusybox(c)
 
 	// Run a few containers on host network
@@ -1285,6 +1296,7 @@ func (s *DockerNetworkSuite) TestDockerNetworkRestartWithMultipleNetworks(c *che
 }
 
 func (s *DockerNetworkSuite) TestDockerNetworkConnectDisconnectToStoppedContainer(c *check.C) {
+	testRequires(c, SameHostDaemon)
 	dockerCmd(c, "network", "create", "test")
 	dockerCmd(c, "create", "--name=foo", "busybox", "top")
 	dockerCmd(c, "network", "connect", "test", "foo")